Antagonistic Activity of Soil Fungal Metabolite Against Candida albicans

Authors:

Prayan Jain (Kurukshetra University, Kurukshetra)

R.K. Pundir (University Institute of Technology and Management, Bhor Saidan, Kurukshetra)

Keywords: Candida albicans, soil fungi, antimicrobial metabolite.

Abstract:

In the present study, soil molds were evaluated far their antifungal activity against three Candida albicans strains. Of the 200 fungal isolates, 10 isolates showed inhibitory activity. Of these 10 isolates, Aspergillus sp. was found to be most effective against all the three Candida albicans strains with zone of inhibition varying between 28mm and 30mm. On comparison, fungal metabolite of Aspergillus was found to be most effective than the commercially available drugs. It may be suggested that antimicrobial metabolite obtained from the soil fungus, might he used in the prevention and treatment of C. albicans infections.